00:00
Ok. So everyone is talking about the new diet drug Ozempic
00:04
which is actually meant it's meant for diabetics technically,
00:07
but people are using it for weight loss.
00:10
the people that have used it have said that it's been very
00:13
effective and it's helped.
00:15
Have you heard of it?
00:17
Oh, yeah, I've heard of it everywhere.
00:19
I feel like for the last year one of my thea,
00:22
ok, I won't expose them exactly who,
00:25
but the doctor told the nurse the wrong dose and she ended
00:30
up overdosing on OIC,
00:32
her do that apparently.
00:35
Yeah, we've never heard of on the news but it happened
00:37
to my t thank God she's ok now,
00:40
but the dose that they gave her was over 100 times the
00:44
dose it was supposed to be.
00:46
So, yeah, she ended up in urgent care real fast
00:49
and she's all good now.
00:51
But that was her first experience with it and she was,
00:54
she using it for like diabetes or weight loss.
00:57
No, she was doing what she was trying to get snatched
01:03
And then so, I mean,
01:04
there's a lot of thoughts on the drug and thankfully we have
01:08
a doctor here with us who's very,
01:09
very, very familiar with Ozempic.
01:12
We have Doctor Rocio Salas Whelan to help us understand Ozempic.
01:18
Hi, doctor. Hi doctor.
01:20
Thank you for having me.
01:21
Thanks for being. Yes,
01:22
thank you for coming on.
01:23
So, can you explain how Ozempic works for weight loss?
01:28
So, Ozempic, the drug is Sema tide and they're synthetic
01:34
hormones that we also make in our gut.
01:36
They're called G LP one.
01:38
And the way that they work for type two diabetes,
01:41
they increase insulin production in the pancreas and makes the insulin that
01:45
the patient makes to work better.
01:48
But for weight loss,
01:49
what it does, it increases your satiety hormones when you start
01:53
eating and you're using this medication.
01:54
So basically you get fuller with half a portion or a third
01:59
of a portion of what you normally would need to get full
02:02
And then in between your meals,
02:04
it suppresses your hunger hormones.
02:06
Really. You feel hungry at one point,
02:08
but you eat a small portion and you're physically satisfied and content
02:12
until your next meal.
02:14
And then in the brain,
02:15
we have receptors for these hormones and they take away the reward
02:20
of food or certain beverages or including alcohol,
02:25
right? So let's say somebody who goes for sweets or carbs
02:29
for some sort of relief or anxiety,
02:32
boredom, depression, it just takes it away.
02:36
So there's no drive for that anymore.
02:39
You eat when you're hungry,
02:40
you enjoy it when you're eating,
02:42
but then you get fuller faster and then the food is out
02:47
Wow. I never thought about the logistics behind it,
02:52
but that makes sense why you would lose weight.
02:55
You're eating a lot less than what you usually would be eating
03:01
what are the risks or side effects that could occur?
03:04
Always say the benefits or the effectiveness and the safety is going
03:09
to depend on who is giving you the medication.
03:13
How much expertise that physician has on using these drugs.
03:18
Because when they're used by the right person or the right doctor
03:22
they're very minimal side effects.
03:25
Right? Sometimes there's a little bit of nausea and that's just
03:28
what while patients get used to the fullness feeling that they weren't
03:32
used to anymore, but really side effects that will make the
03:37
medication be stopped or like your aunt that need to be taken
03:40
to the hospital or go to urgent care can be prevented if
03:46
who's giving you the medication has expertise on these drugs.
03:50
And, and how long does it take to see weight loss
03:53
result on Ozempic? Really?
03:56
In the first few weeks,
03:57
we can see significant weight loss.
04:00
Now, we're not whenever we're doing weight loss treatment and this
04:03
could be with medications,
04:04
with our medications, we're never looking for a quick,
04:07
rapid weight loss, right?
04:09
Weight loss should be more of a marathon and not a sprint
04:14
And the ideal weight loss is anywhere from 1 to £2
04:17
per week again with medication or without medication because more than that
04:23
the person is losing muscle mass.
04:25
And we don't want that.
04:27
We don't want the person to lose muscle mass because the muscle
04:31
loss is what slows down the metabolism when somebody loses weight.
04:37
That definitely makes sense.
04:38
So recently, I feel like it's been super popular and on
04:42
the news maybe because of celebrities or whatnot.
04:45
But is the drug new or has it been around for a
04:49
while? It is not new and Osmic became the poster child
04:53
of this class of drugs.
04:55
But we have the first FDA approved in its class was in
04:58
2005 by the name of Valera.
05:01
Then it came as Picosa in 2010 and then Osmic in 2017
05:07
And then most recently we have Monro and Zon which is
05:11
Tide and I like to explain them as iphones,
05:14
right? We have the iphone 13 that is Zend and VSA
05:18
We have the iphone 14 which is Osmic and now we
05:21
have the iphone 15 which is Monro and Sepa,
05:24
right? So every generation of them will come safer and we
05:28
see more weight loss on the newer drugs and different drugs.
05:35
So they're they're the same drug.
05:38
But you see like as example,
05:40
Ox OEC is Sema Osmic has the FDA approval for type two
05:45
diabetes, but Sema also named as wo is FDA approved for
05:51
weight loss without diabetes.
05:53
So they're not exclusively type two diabetes drugs.
05:57
Now they are FDA approved for weight loss,
05:59
they just changed the name,
06:01
but it's the same drug,
06:02
same dosing, same pen,
06:04
same effects, but they still call it Ozempic Porque.
06:11
So, for the newest form of Ozempic,
06:14
is that the same form of injection?
06:18
It's a once a week injection and it's tide as the drug
06:23
and that medication definitely we're seeing significant more weight loss and less
06:28
gastric side effects. So almost no nausea compared to older drugs
06:32
also. Who do you think should be taking these drugs for
06:36
weight loss is patients that have a BM I of seven or
06:40
above and one comorbidity from their weight.
06:44
So high blood pressure,
06:45
sleep apnea, joint pain or patients that have a BM I
06:50
equal or greater than 30 we're moving away from the BM I
06:54
slowly but unfortunately, insurance still will make their decision according to
07:00
BM I. So insurance covers these,
07:04
these weight loss. Most commercial insurances Medicare is starting to cover
07:10
with OB and Osem for type two diabetes right now.
07:13
So slowly more insurance are starting to implement them in their plans
07:17
Well, how much is it without insurance?
07:19
It's around $1100 for a month supply or if the person has
07:25
commercial insurance and it's not approved by the insurance,
07:28
there's coupons that the pharmaceuticals have and it comes to about 500
07:33
per month. So half of what out of pocket costs.
07:38
I did too and you explained it so well.
07:41
I love it. I love how you explain everything.
07:44
Thank you. Thank you so much,
07:45
Doctor. We appreciate having you on the show and really giving
07:49
a breakdown of how Ozempic works and where can we follow you
07:53
Where can people find you?
07:55
Well, on Instagram is at Dr Sala Whelan,
07:58
Drsalas Whelan or also on tiktok.
08:03
It's New York Endocrinology or my web page is NY endocrinology.com.
08:08
Thank you so so much for informing us and having this conversation
08:12
with us today, doctor.
08:13
Thank you. You're very welcome.
Series